We are poised to take major steps forward in H.I.V. vaccine research if the effort receives the support it needs.
My meeting with Dr. Ditiu and subsequent conversation with Dr. Raviglione, director of WHO's TB programme, gave me reason to believe this progress will continue, but ultimate success will take two major efforts: one from individuals -- people must get promptly tested, get treated, and, when necessary, get prophylaxis, so that we can prevent others from getting the disease.
Though she is susceptible to the upset, it will take a major effort to remove Kvitova from the tournament.
"It would take a major effort to make up for that loss," Wiehe said.
One thing's for sure: It would take a major effort to remove the estimated 5,000 encamped to stop the construction of the Dakota Access Pipeline.
It will take a major effort in multiple sectors of our society to deal with the violent elements in our midst.
"But it's going to take a major effort to convert what is an extraordinary amount of enthusiasm, dedication and support into campaign contributions".
A senior Pakistani officer who is overseeing the relief efforts, Lt. Gen. Nadeem Ahmad, estimated reconstruction costs in the war-ravaged areas at $2.5 billion, and said it would take a major effort by the government, aid groups and private donors to return all the displaced successfully and rebuild their communities.
It can take a major effort to gain the support of administrators.
"It took a major effort, changes in zoning, and getting legislation passed to make this work," Mr. Deller said.
