First, for a known problem with a known solution — such as customer segmentation and propensity modeling for targeted marketing campaigns — the company could take a hypothesis-based approach by starting with the outcome (e.g. cross-sell/up-sell to existing customers), pilot and test the solution with a control group and then scale broadly across the customer base.
We take a hypothesis-free approach to identify genetically influenced NMR features and investigate whether specific ratios between NMR intensities at two chemical shifts can provide informative and robust biomarkers.
The second is to take an hypothesis-driven approach to generate gene sets based on knowledge of the pathways involved in resistance and sensitivity to individual drugs that can then be correlated with in vitro chemosensitivity data or clinical outcome (Kikuchi et al, 2003).
The synthesis of functional magnetic resonance imaging (fMRI) and genome-wide data takes a hypothesis-free approach as to which genetic variants are of interest.
We took a hypothesis-testing approach.
Unlike previous methods, the functional gene group approach does not rely on post hoc formulation of pathways or networks, but instead takes a hypothesis-driven approach by directly testing functional gene groups.
"What they've done is take a serious hypothesis about how the T rex worked, based on good evidence," she says.
Some -- by no means all -- economists trying to understand growing inequality have begun to take seriously a hypothesis that would have been considered irredeemably fuzzy-minded not long ago.
Advance a hypothesis, take a stab at finding proof, then try to replicate the results if successful — or, if not, try again.
"We take a bet on a hypothesis and it's unclear if users will engage with it or whether or the ecosystem will build around it, but we're actually trying to transform the experience to be more fun, more innovative, and make our lives more convenient," explained Moorjani.
