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Researchers on the STRIDE research team will use these inputs (daily steps, RPE during walking and daily affect) to generate individually tailored target steps/day for the following week that maintain exertion at between RPE 11 (light) and 13 (somewhat hard) on the RPE scale, the "bandwidth" within which people have the most positive response to exercise [ 40- 42].
Whereas the immunomodulatory therapy would release the brakes of the immune system, the individualised vaccine approach would instruct the immune system by providing a tailored target map to maximise anti-tumoural effects.
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This has mainly resulted from the identification of molecular alterations in relevant intracellular signaling pathways—Hedgehog, PI3K/AKT/mTOR, Notch, ErbB, MAPK and angiogenesis which are potential tailored targets for gallbladder cancer patients.
Resistance exercises were individually tailored, targeting the major muscle groups for upper and lower limbs.
Research to identify pregnancies at higher risk for PTB is vital to develop tailored, targeted interventions to prevent PTB occurrence; a recent Cochrane review recommended evaluation of a risk screening tool to predict PTB [ 5].
110, 112 Although the detection of ctDNA harboring mutations leading to resistance to EGFR inhibitors represents a promising technology for less invasive methods of tailoring targeted therapies, it has not yet been validated for CRC.
Tailoring targeted wards and was informed by problem-focused interviews with physicians and chief nurses (response rates: 100%) and a written survey which assessed HAPA-factors (physicians: 71%; nurses: 63%).
The topics included Risk Factors, Tailored Targeted Therapy for All - A Realistic and Worthwhile Objective, The Potential of New Technologies/Approaches, Who Would Have Thought It! and Are Current Drug Development Programmes Realising the Full Potential of New Agents?
Furthermore, like HDL (Corbin et al. 2007), HPPS can be tailored to target a receptor of choice by introducing various targeting ligands for different cancer applications.
The proposed CDR is tailored to target the optical network standard OC-192.
In general the band ([omega_{L},omega_{c}]) may be tailored to target specific spectral regions in the noise PSD.
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