One-sentence summary for table of contents: Recommendations are needed for management of potential laboratory exposure to a Biosafety Level 4 pathogen.
For example, 25 key items were identified for HIV guidelines from the WHO 2010 guidelines for the management of HIV/AIDS in adults and adolescents(19); all current HIV management guidelines should include these and would score 100% if all 25 points were identified (Table 2; tables for list of recommendations for all reference guidelines are available on request).
A new system was developed to grade both the overall quality of the evidence (Table 2) and the strength of recommendations (Table 3).
In international meetings for over 8 years, the GRADE Working Group has developed a set of evidence-based criteria to grade the quality of evidence (Table 1) and the strength of recommendations (Table 2) (Schunemann et al. 2006b, Guyatt et al. 2008a).
In a series of 16 international meetings and correspondence over five years the GRADE Working Group has derived a set of criteria to assess the quality of evidence (Table 1) and the strength of recommendations (Table 2) [ 25, 29, 35, 36, 41, 42].
Higher scores on attitude, self-efficacy, and intention of some of the lifestyle behaviors were the strongest correlates with adherence to an increasing number of recommendations (Table 6).
An additional 30% allows more room for foods that do contribute to the intake of these nutrients on top of recommendations (Table 2).
53 We will present our key findings in a 'summary of findings' table using the Grading of Recommendations, Assessment, Development and Evaluation (GRADE) approach, 54 addressing the quality of evidence, estimated effect sizes, and the secondary objectives outlined above.
The MAPS statement is a 23-item checklist of recommendations (Table 1) that we consider essential for complete and transparent reporting of studies that map onto generic preference-based outcome measures.
The IDEAL Collaboration developed a framework for the stages in surgical innovation (idea, development, exploration, assessment, and long term study; table) and a set of recommendations on how evaluation should be conducted at each stage (box 1).
