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Once an E-value threshold is chosen, a user is presented with a table of pathways available for the chosen species; only pathways with matches based on the threshold the user has selected are presented.
The resulting sortable ranking table of pathways contains the test statistics and significance scores, the number and identifiers of the mapped genes/proteins, and buttons to generate box plots for each pathway and forward the genes/proteins to other bioscientific web services for further analysis.
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The current study aims to identify common pathways associated with diabetes traits by analyzing dbGaP GWAS data, and we expect that the high specificity of USGSA using an independent distribution table of pathway associations will make the findings replicable and comparable among studies.
12284_2013_52_MOESM1_ESM.xlsx Additional file 1: Table S1: List of pathways that have undergone manual curation.
Furthermore, as each list of differentially expressed pathways is produced, tables of all pathway names and significance values are saved for future reporting.
Description: Table of all metabolic pathways in X. bovienii and the relative completeness of each pathway.
Table of top activated pathways of selected gene sets.
Cell adhesion (GO 0007155) is significantly over-represented in the YAC128 striata over this time period.> -wrap-foot> The probesets and genes that were significant over time are given in Table S1 and the full list of pathways in Table S2.
Examples of these studies are summarized in Table 3. aFor gene abbreviations and explanations of pathways, see Table 5. Proteomics is the large-scale study of proteins, allowing analyses of the entire complement of proteins in a cell or sample simultaneously, and made possible today by technological advances in computing and data processing.
Although the numbers of essential genes in the five strains are slightly different, these essential genes have the same number of pathways (Table 1).
Examples of recent proteomic studies of osteoporosis are summarized in Table 4. aFor gene abbreviations and explanations of pathways, see Table 5. Epigenetic regulation is important for sustaining normal growth and development of animals [ 91].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com