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Only recently has progress been made to make possible the use of some of these model systems to dissect the genetic basis of regeneration [ 4].
His laboratory has used various imaging systems to dissect several endogenous molecular pathways, including activation of hypoxia-inducible factor α in xenografts using a hypoxia-responsive promoter that drives expression of green fluorescent protein.
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The newly designed Dissect-O-Matic is a fully automated system to dissect, block, stain, and mount biological samples for microscopy imaging.
Our data demonstrate that the M. incognita-rice pathosystem may be a novel additional model system to dissect the complex cellular and molecular nematode interactions with monocotyledonous host plants.
Here, we utilized a promoter GFP transformation system to dissect promoter region of sphinx and to investigate its expression pattern in relation to its function.
gambiae gSG6 may represent an excellent model system to dissect molecular and cellular events leading to immune tolerance to insect saliva in humans.
As such, behaviors in this assay could serve as a simple model system to dissect natural variation in the insect decision-making circuit.
Arabidopsis is also an outstanding model system to dissect the interplay between small interfering RNAs (siRNAs), DNA methylation and histone modifications [19] [23].
In summary, this study presents a novel and unique in vitro system to dissect aspects of the latency/reactivation cycle of wild type alphaherpesviruses and points to IFNalpha as a potential driving force in efficient alphaherpesvirus latency establishement.
An important future challenge is to establish the full spectrum of Drosophila plasmatocyte heterogeneity and exploit the utility of the Drosophila genetic system to dissect the mechanisms that regulate such leukocyte plasticity.
Our results regarding the in vivo inhibition of T-cell allostimulation in animals xenografted with human tumors offer a useful experimental system to dissect tumor-dependent mechanisms of inhibition that are operating distantly from the tumor implant.
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