Sentence examples for systems recapitulate the from inspiring English sources

Therefore, in line with previous reports, our data indicate that stepwise tumorigenesis systems recapitulate the tumor selectivity reported for TRAIL.

In fact, one interesting aspect of TDP-43 biology is that many of the effects of human TDP-43 expression in model systems recapitulate the effects of overexpression of endogenous orthologs, despite the low degree of conservation of the C-terminus from the perspective of an Altschul alignment (Altschul et al. 1990).

We describe the features and properties of biomimetic delivery systems, recapitulating the distinctive traits and functions of viruses, exosomes, platelets, red and white blood cells.

In this scenario, premature aging disorders in humans and the various animal model systems recapitulating the phenotypes of accelerated aging and cellular senescence constitute a major area of interest in understanding the intricacies of the process of aging.

To better understand the molecular mechanisms leading to aberrant splicing of IKBKAP mRNA in FD, creation of model systems recapitulating the pathological development of neural cells is required.

Although bidimensional systems represent a helpful mean to analyze ECM stem cell interplay in vitro, the great challenge is the recreation of 3D systems recapitulating the in vivo condition  [105,106].

We demonstrate that this culture system recapitulates the hepatic sinusoid microarchitecture including functional bile canaliculi and complete cell polarization.

Our experimental system recapitulated the early phase of DMD pathology as demonstrated by visualisation and quantification of Ca2+ influx using intact myotubes differentiated from hiPS cells.

The integrated smoking system recapitulates the complex oxidant-induced biological responses of normal lung cells to toxic molecules present in cigarette smoke as well as COPD-specific inflammatoresponsesses.

This novel cellular system recapitulates the key features of PD namely dysfunction and death in ageing midbrain neurons.

Upon exposure to 1.5 mM calcium, they undergo a differentiation program which closely resembles that of the epidermis; this well documented system recapitulates the natural epidermal calcium gradient [30], [31].