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The lambda repressor and its associated proteins became one of the best understood systems of gene regulation and helped him and other researchers understand the process in many higher organisms.
In fact, regulatory systems of gene expression acting at both the transcriptional and translational levels are well represented in the chlamydial genome, including homologues of endoribonucleases E, III, G and P, exoribonucleases II and PNPase, and oligoribonuclease [8], [9].
Applying these straightforward abstractions to cellular processes has gained currency throughout the biosciences, so much so that a network mind-set has become a necessary precondition for thinking about systems of gene regulatory interactions.
Luciferase reporter systems are widely used as sensitive, quantitative, and convenient measurement systems of gene expression in living cells [ 3].
These data support the hypotheses that DNA methylation either occurs as a consequence of the chromatin environment only in some genes, or that two redundant and independent systems of gene repression have evolved.
Several pharmacologically regulated systems of gene expression have been developed, including the tetracycline system, which uses the bacterial components of tetracycline resistance in a synthetic system that functions efficiently in eukaryotic cells [ 7, 8].
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The Gibbs implementation of CSI and Gibbs implementation of hCSI unfortunately inherit these same scaling issues, making them useful for small systems of genes, but less so for much larger systems.
By clarifying what was happening, they discovered an unexpected system of gene regulation in living cells and began an explosive phase of research in a field known variously as RNA interference or gene silencing.
GO is an international standardized classification system of gene functions.
Among them, the Polycomb group (PcG) of proteins is an essential system of gene silencing involved in the maintenance of cell identities during differentiation.
For example, melanins are black, brown, tan, or reddish brown pigments whose production and deployment involve a complex system of gene products and biochemical pathways.
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