Sentence examples for systems expression of from inspiring English sources
In other systems, expression of α1-PDX in tumor cells blocked the maturation of MT1-MMP, leading to reduced MMP-2 activity and cell invasion [22].
Despite the undoubted value of these culture systems, expression of transgenes in vivo does not always recapitulate expression observed in culture.
Here we show that, in three distinct experimental model systems, expression of an N-terminal fragment of APC (N-APC) results in loss of directionality, but not speed, of cell motility independently of changes in β-catenin regulation.
In other systems, expression of defective myosins lacking a functional motor domain results in cessation of movement of the normal cargo carried by the particular myosin, a dominant negative phenotype [ 27].
Similar to studies using other neurotrophin delivery systems, expression of BDNF by adenoviral vectors in combination with electrical stimulation from a cochlear implant promoted SGN survival and improved thresholds for SGN stimulation [ 142].
On the other hand, β-synuclein is believed to be a neuroprotective factor in several experimental in vivo systems, expression of this protein ameliorated neuronal pathology caused by overexpression of α-synuclein (2– 7).
These mice have increased nervous system expression of a regulatory subunit of the CGRP receptor, human receptor activity-modifying receptor (hRAMP1).
In our experimental system, expression of CD11b on peripheral leukocytes was significantly downregulated after GMA treatment.
Fetal sympathetic nervous system expression of NESP55 was shown to be specific for chromaffin cell types.
Neurexin expression was prominent in the nervous system of filleted embryos, consistent with strong nervous system expression of neurexin and the fact that the nervous system is many cell layers thick.
However, using the modular UAS/GAL4 system [16], they can be rescued by nervous system expression of an endoA transgene, UAS-endoA, driven by the pan-neuronal transcription initiation protein elav-GAL4.
