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Both gene systems demonstrate a potential evolutionary mechanism that can convert myb transcriptional activators into repressors.
To summarize, past theoretical investigations into scaffold-free MAPK systems demonstrate a tendency towards a biphasic response, while systems involving a scaffold show in theory a strong and robust graded response, which is contrary to the recent experimental findings.
Unfortunately this score, as well as the more complicated scoring systems, demonstrate a significant degree of variability in their ability to predict the need for massive transfusion.
Most widely used CO monitoring systems demonstrate a mean percentage error of around 40 to 45% [ 103] and most of these devices present with concordance <92%.
Overexpression of several MMPs has been described in breast cancer [ 21, 22] and both in-vitro and in-vivo systems demonstrate a role for MMP in mediating breast cancer cell invasion [ 23, 24].
39 40 In summary, longitudinal illegal drug surveillance systems demonstrate a general global pattern of falling drug prices and increasing drug purity and potency, alongside a relatively consistent pattern of increasing seizures of illegal drugs.
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Although most systems demonstrate an image quality that is superior to existing film screens, some are inferior.
Prior studies of active pectoral implantable defibrillator (ICD) lead systems demonstrated a lowering of defibrillation thresholds (DFTs) with the addition of a superior vena cava (SVC) coil.
This NLSC was examined both numerically and experimentally via substructure tests of nonlinear single-degree-of-freedom (SDOF) systems demonstrating a base-isolated structure.
Both assay systems demonstrated a significant increase in AICD nuclear signaling following PBA treatment, while stress induction by thapsigargin induced a repression in nuclear signaling (Figure 10A-C).
Thus, in vitro data from other model systems demonstrating a role for Nod2 has been consistent with prior observations with B. burgdorferi [17], [25], [55] [57].
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