DOI: http://dx.doi.org/10.7554/eLife.02164.022 Through the use of mouse genetics, lineage-specific mosaicism, embryonic stem cell systems, and ex-vivo organ culture, we have shown the existence of an undifferentiated and expansive population of CPCs and their microenvironment during development, which may provide a stem cell-niche paradigm in cardiovascular biology.
Conservation of plant diversity is a massive task if viewed globally, but the combination of a well-designed and well-managed protected area system and ex situ gap-filling and back-up should work anywhere.
A series of new derivatives of the clinically used aminoglycoside antibiotic paromomycin were designed, synthesized, and their ability to read-through premature stop codon mutations was examined in both in vitro translation system and ex vivo mammalian cultured cells.
Dwayne Wade's ex-wife Siohvaughn Funches-Wade took to the streets of Chicago to air her frustrations with the court system and her ex-husband.
"If I had the ability, which nobody does really, to just design the system and say, ex cathedra, this is what we're going to do, you would cut the number of teachers in half, but you would double the compensation of them, and you would weed out all the bad ones and just have good teachers.
In addition, the journal is a medium for the publication of interdisciplinary studies on the interactions between natural fluid systems and their boundaries (ex. air-water surface exchanges, bottom sedimentation and resuspension, and exchanges between surface and subsurface waters) as well as interactions between fluids and their contents (ex. chemical and biological loads).
We also examined the use of models to represent production systems and to evaluate ex-ante the impact of innovations on these systems' functioning and performance.
In the cases of perennial plants analysed, managed in situ populations are sources of materials for home gardens and other systems of ex situ management and, therefore, domestication under in situ management is closely related to domestication under ex situ management (Casas and Caballero, 1996; Casas et al., 1999 b, 2006).
In the present study, we determined stem cell specific marker gene expression of SP cells in bovine synovial membrane, and constructed a culture system for efficient collection and ex vivo expansion of the stem cells.
The HBP has been demonstrated to be an essential signaling system in the failing heart (Watson et al, 2010), and accumulating evidence from in vitro and ex vivo systems shows that augmented O-GlcNAc levels via the HBP potentiates cytoprotection (Ngoh et al, 2010; Darley-Usmar et al, 2012).
