Sentence examples for systems activation of from inspiring English sources

However, in other model systems, activation of JNKs and p38mapk (also known as stress activated protein kinases) can mediate apoptosis (Xia et al, 1995; Chen et al, 1996; Verheij, 1996; Zanke et al, 1996; Bossy-Wetzel et al, 1997; Behrens et al, 1999; Tournier et al, 2000).

Resistance involves numerous mechanisms including decreased drug uptake, increased drug efflux along with reduction of intracellular drug concentration, activation of detoxifying systems, activation of altered DNA repair mechanisms, evasion of drug-induced apoptosis, induced emergency response genes to impair apoptotic pathway, etc.

In mouse and human systems, activation of both AKT and ERK signaling is commonly observed during the initiation and progression of PCA[26], [43].

In cell-free systems activation of calpain is Ca2+-dependent, but a role for Ca2+, or indeed another divalent cation, in stimulating calpain in intact immune cells such as T cells has not been examined.

In addition to disruption of protein degradation systems, activation of oxidative stress can induce P-S349.

Systemic lupus erythematosus (SLE) is an autoimmune disease with chronic or episodic inflammation in many different organ systems, activation of leukocytes and production of pro-inflammatory cytokines.

In addition and of particular interest for our model system, activation of AMPK was found to activate the unfolded protein response [ 54] and to lower ER stress induced by various stressors [ 49].

Zn is essential element, involved in the immune system, activation of many enzymes and the growth.

Generally, aPL may activate platelets, endothelial cells, and monocytes, leading to the inhibition of the fibrinolytic system, activation of the coagulation cascade, and possibly activation of the complement system [16].

Schmid factor analysis shows that the "zigzag" slip bands result from one primary slip system activation of threading dislocations propagation within the twin lamellae, which is fundamentally different from that of polycrystal materials.

In this system, activation of the terminal myogenic differentiation program is simply accomplished by withdrawing mitogens from the culture medium.