Sentence examples for systemically modified from inspiring English sources

The properties of M-13 bacteriophage can be systemically modified to impart target-specific selectivity and sensitivity using the phage display technique.

It has been documented that probiotics can act locally in the oral cavity through the biofilm and systemically by modifying the immune response [ 20].

The findings reported here indicate that ligand modified nanoparticles given systemically or intratumorally at low concentrations can significantly attenuate subcutaneous B16-F10 tumors in mice after repetitive short AMF exposure.

Rehling et al 18 found that renal dynamic imaging gave more accurate values than the renal clearance of inulin, whereas Zuo et al 19 indicated that the plasma clearance of DTPA was systemically higher than that of modified inulin.

Soskolne said, "We're trying to systemically change things".

Mice have been genetically modified to lack sod2 in specific tissues [1], [4], or systemically in multiple genetic backgrounds [5], [6].

RT-PCR and nucleotide sequence analysis of the CMV progeny showed that the modified leader sequences were retained in RNAs extracted from systemically-infected leaves (data not shown).

We expressed unilaterally in mouse striatum a modified heteromeric ivermectin (IVM -gated chlorIVM -gatedl from chloridens (Gluchannelsystemically administered IVM, and then assessed amphetamine-induced rotational behavior.

In a therapeutic model, when modified mRNA encoding herpes simplex virus 1-thymidine kinase (HSV1-tk) was systemically delivered to H460 xenograft-bearing nude mice, it was significantly more effective in suppressing tumor growth than pDNA.

Regulators did not identify the 28 systemically important financial institutions, saying that the list could change if the proposals were modified or banks reorganized.

CPI and variants of it may be therapeutically useful not only because of its broad inhibitory range but because it can be readily modified to permit targeting to specific cell types, thus avoiding toxicity associated with systemically administered small molecular protease inhibitors.