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This paper gives an insight into the systemic variation of the bulk motion in a high shear mixer (HSM) equipped with a three-blade impeller.
Metabolomics is a holistic study aimed at identifying and quantifying metabolites, which are notably sensitive to systemic variation and altered metabolic pathways.
On the other hand, within these contextual components (field, tenor and mode) there is a systemic variation in the relative prominence of different options, which causes a functional variation in the language, i.e. register.
Figure 4 shows the basic proposal, in which the objective is to utilize the NMS algorithm, adding noise conditions in each vertex, as an analogy with the Taguchi´s crossed array, this is to "penalize" the operative conditions with the systemic variation (noise).
Similar to these studies, we scaled the data within each set to the mock transfection (0% derepression, equivalent to an average reduction of ∼2.5-fold on mRNA and ∼5-fold on protein level), and let-7 anti-miR controls served as a reference for 100% derepression (see Fig. 1B), to account for this systemic variation in the set-point of repression.
Non-biological influences and systemic variation were corrected using a normalisation algorithm.
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The use of an input function for quantitation of biological function seeks to reduce many effects due to systemic variations.
The use of K i, however, was supposed to better account for the systemic variations in 18 F-FDG delivery between studies or animals.
All cell types were characterized for epithelial origin and growth patterns and following optimization of dosing strategies and assay procedures, a strict study design was implemented to avoid systemic variations.
Of these regions, the NAcc and the dSTR are among the most enriched areas of the brain [30], and they are sensitive to systemic variations in iron (i.e. dietary restriction or supplementation), which in turn affect DA neurotransmission.
In fact, brain DA regions are known to be enriched in iron [73], [74] and susceptible to systemic variations of this nutrient [75], suggesting that specific effects of inflammation and iron supplementation may be found in the mesolimbic DA neurons, which would then be involved in the induction of the marked effects on DA function observed in the adult offspring.
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