Sentence examples for systemic vaccination from inspiring English sources
Systemic vaccination with C. difficile toxoid vaccines have been shown to generate high levels of serum antibodies that appear to reduce the potential for relapse.
Alum (aluminum hydroxide, phosphate, or hydroxyphosphate) has an excellent safety record for systemic vaccination.
Human immunodeficiency virus (HIV -1 Tat protein induces protection in non-HIV -1primaTat uproteinteminducesination.
Distinguished from systemic vaccination, mucosal vaccination normally induces strong secretory IgA response to defend the viral infection at the mucosal surface, besides producing systemic serum IgG to neutralize the newly generated viruses (Renegar et al., 2004).
Memory CD8+ T cells elicited by local intranasal, but not systemic, vaccination with an engineered non-replicative CD8+ T cell-targeted antigen confer enhanced protection to a lethal respiratory viral challenge.
Vaccination studies in mice revealed that the Tf-gp140 conjugate elicited high titres of CN54gp140-specific serum antibodies, equivalent to a systemic vaccination, when conjugate was applied topically to the nasal mucosae whereas gp140 alone was poorly immunogenic.
Following a combination of two mucosal and two systemic vaccinations of mice, we found significant enhancement of both local and systemic antibodies as well as cytokine responses.
Early studies, in which mucosal vs. systemic vaccinations were compared, indicated that only the production of mucosal responses through a combination of systemic and mucosal immunization limited these symptoms.
Participants were asked to document clinical symptoms (local and systemic) after vaccination in a three-week diary.
As it has been described that systemic BCG vaccination of mice leads to the dissemination of BCG throughout the body including the lungs [15], [16], one could further hypothesize that this effect was induced by the presence of live BCG in the lungs of vaccinated mice.
Vaccine-induced TEM responses have been associated with protection against viral pathogens (17), and TEM populations have been investigated and detected following systemic BCG vaccination (18).
