Sentence examples for systemic susceptibility from inspiring English sources

The concept of generalized and systemic susceptibility is supported by studies indicating a subset of patients with polyarticular disease known as GOA.

The development of OA may be related to a combination of local joint-specific factors acting in the context of systemic susceptibility.

These subsets of OA fall into two broad groups: those causing biomechanical loading or instability at a specific joint, and those influencing generalized and systemic susceptibility to the process at multiple joints.

Our study describes an in vitro iPSC-based platform for studying the multi-systemic susceptibility to distinct mutations in lamin A/C that could be used as well for testing compounds aimed to correct the abnormalities.

Thus PTPN22 C1858T polymorphism, which is associated with systemic sclerosis susceptibility, reduced the risk of Crohn's disease.

Genome-wide association studies have linked several single nucleotide polymorphisms in Atg5 to systemic lupus erythematosus susceptibility [99].

The early growth response 2 (Egene gene is considered a good candidate for systemic lupus erythematosus susceptibility (SLE).

Knee OA results from increased joint loading acting within the context of systemic and/or local susceptibility [ 4].

These data are consistent with recent studies of systemic lupus erythematosus susceptibility confirming the presence of several independent genetic contributions to autoimmune rheumatic diseases arising from 6q23.

In humans, the lower copy number of MHC is associated with the risk of systemic lupus erythematosus susceptibility (Yang et al. 2007).

In the paper by Dieguez-Gonzalez and colleagues in the present issue of Arthritis Research & Therapy, the results of a detailed genetic investigation of the recently identified rheumatoid arthritis and systemic lupus erythematosus susceptibility region at 6q23 containing the TNFAIP3 gene are reported.