In rodents, systemic administration of single dose of pilocarpine, a muscarinic cholinergic agonist, lead to status epilepticus (SE) and, after a seizure-free period, to a chronic condition determined by spontaneous recurrent seizures (SRS).
Second, collaborating with scientists from the Vaccine and Infectious Disease Research Organization (VIDO -InterVac (International VIDO -InterVac), a combInternational Vaccine Centredeveloped for potent induction of immunity to a pertussis vacombination single dose systemic adjuvantion.
Objective To compare single dose systemic methotrexate (50 mg/m2) with laparoscopic surgery for the treatment of unruptured tubal pregnancy.
Objective To compare the direct and indirect costs of single dose systemic methotrexate with laparoscopic surgery for the treatment of unruptured ectopic pregnancy.
Our data demonstrate that the systemic administration of a single dose of GIDIL2, two weeks post B16F1 implantation, had a significantly superior effect than its parental, non cytokine-expressing, strain (known as BRD509E).
Expectant management is compared with systemic MTX in a single dose intramuscular regimen (1 mg/kg) in an outpatient setting.
The primary outcome measure is an uneventful decline of serum hCG to an undetectable level (< 2 IU/l) by the initial intervention strategy, i.e. expectant management or a single dose systemic MTX.
This RCT will provide evidence whether expectant management is an alternative to systemic MTX in a single dose im regimen in women with an EP with low but plateauing serum hCG concentrations or persisting PUL.
In another open-labelled trial (LRO320), 15 of 18 enrolled Caucasian children with systemic JIA received a single dose of either 2 mg/kg (n =4), 4 mg/kg (n =6), or 8 mg/kg (n =5) tocilizumab by infusion.
