The hematological system is also implicated in myogenesis [ 39- 43], which probably reflects the systemic requirement for muscle function during fetal development.
Since the TICS scales were developed based on the systemic requirement - resource model of health [ 14], the authors postulated content validity as a logical consequence [ 17] with factorial validity being more of a concern.
According to the systemic requirement - resource model of health [ 14], individual health might be promoted and preserved when high internal demands and external demands can be satisfied via employing the available internal or external resources [ 15].
In accordance with the systemic requirement - resource model of health [ 14], these nine factors can be grouped into High Demands referring to specific job conditions and social conditions, and Lack of Satisfaction of one's needs due to unsatisfactory job conditions and social conditions (see [ 17], pp. 38-39).
We designed a trial to determine the efficacy of subtenons lidocaine injection at reducing postoperative pain and systemic analgesia requirements.
The levels of ovarian hormones coordinate these effects with systemic developmental requirements.
Many of these studies report significant reductions in systemic heparin requirements, but are not heparin free [ 3, 4, 7].
Systemic analgesic requirements were reduced during the initial five postoperative days in patients assigned to diclofenac (intramuscular morphine equivalents: placebo = 5.3 ± 4.3 mg vs. diclofenac = 3.6 ± 3.3 mg).
In concordance with this dual function, its expression is modulated by systemic iron requirements and inflammatory stimuli, as it is induced by cytokines such as IL-6 [ 3].
