Sentence examples for systemic reconstitution from inspiring English sources

A successful systemic reconstitution with human immune cells including functional T cells as well as development of tumors infiltrated with human T and natural killer (NK) cells was observed.

Particularly relevant to this study is the broad and systemic reconstitution of BLT mice with human immune cells necessary for HIV-1 replication and transmission (CD4+ T cells, macrophages and dendritic cells) that encompasses the peripheral blood and the rectal and vaginal mucosa rendering BLT mice susceptible to intravenous and mucosal HIV-1 infection [22], [24], [26].

For systemic MC reconstitution studies, BMMCs were transferred into 10-week-old Kit W-sh/W-sh females by i.v. injection of 5 × 10 cells in 200  μl of PBS in the morning of two consecutive days (in total 1 × 10 cells) through the tail vein.

Humanized BLT mice are individually bioengineered to exhibit a complete, systemic, self-renewing reconstitution of all major human hematopoietic lineages including T, B, monocyte/macrophage, dendritic and natural killer cells that facilitates the generation of functional human immune responses [22] [26].

We demonstrate that MCs are present at the fetal maternal interface after systemic and local reconstitution, suggesting that MCs act locally to foster normal pregnancy.

Although the pathologic immune responses occur in the eye, immune dysregulation that allows for development of pathologic responses is presumably caused by faulty systemic immune cell reconstitution.

Despite our study was not designed to identify statistically significant associations between peripheral blood microbial genotypes and immunological outcome, these findings highlight the potential correlations between the bacterial species in the systemic circulation and immune reconstitution.

It usually begins unilaterally, but without immune reconstitution or systemic treatment, bilateral disease ensues almost universally.

Systemic and local MC reconstitution of Kit W-sh/W-sh mice led to increased uterine expression of several molecules, for example, uPA and tPA, both related to implantation.

Should this supposition be verified, the next question to be addressed would be whether systemic microbiota may affect immune reconstitution.

Taken together these results suggest that patients developing symptoms within the first 12 weeks after starting cART experience enhanced sub-clinical inflammation and immune reconstitution in the systemic compartment compared to those remaining symptom-free.