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The first year pathology, MED 102, is related to the teaching of general pathological concepts serving as a foundation to the upcoming systemic pathology taught in second (MED 202) and third (MED 302) year courses.
Systemic pathology may be caused either through direct virus-mediated infection or by indirect mechanisms such as 'by-stander' apoptosis.
Burns are difficult to treat, wounds with complex local and systemic pathology and high mortality, that often heal slowly with scars and contractures.
Additionally, the physiological window for knee health is thought to be highly individual and may be influenced by genetics, sex, lifetime loading history, presence of prior injury/scar tissue, systemic pathology, and local anatomy [15].
Corynebacterium diphtheriae produces diphtheria toxin, which is responsible for the systemic pathology associated with diphtheria, whereas Vibrio cholerae produces cholera toxin, which is responsible for the diarrheal pathology associated with cholera.
At the time of the necropsy, there was little evidence of systemic pathology.
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Salivary biomarkers of oxidative stress reflect local and systemic pathologies and may inform on the diagnosis, prognosis, and therapeutic responsiveness of numerous human diseases.
Moreover, MSCs can be transduced with retroviral and other vectors and are, thus, potential candidates to deliver somatic gene therapies for local or systemic pathologies.
Patients with serious concomitant disease, systemic pathologies, symptomatic headaches, a current or prior history of drug/alcohol or strong opioid [23] abuse, pregnant or breastfeeding and aged <18 or >65, were excluded.
Bone and cartilage turnover is coupled during some systemic pathologies such as postmenopausal osteoporosis and osteoarthritis.
Particular attention must be placed to rule out and correct invalidating systemic pathologies.
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