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Lastly, the methodology applied in the ATM domain presented in this paper is equally transferable to systemic modelling of other complex socio-technical systems.
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S. aureus acquires heme-iron using the iron regulated surface determinant (Isd) system and the heme transport system (Hts) with both systems showing critical importance in systemic models of infection.
In addition, both the Hts and Isd systems are individually required for full virulence in systemic models of staphylococcal infection [2] [4] however their combined contribution to pathogenesis has not yet been elucidated.
This pools-and-proteins approach naturally compiles the wealth of available molecular biological data into a systemic model and can easily be extended to describe other systems by adding new protein or nucleic acid types.
Systemic models have the advantage of allowing the study of heterogeneous, complex karst systems without relying on extensive geographical and meteorological datasets.
A change in a small part of a complex network can affect the overall capabilities of a system, such as metabolite production, which can be impossible to predict without a systemic model.
Drayton Park, to use the jargon, follows a "systemic" model rather than a "medical" one.
But none completely explain behavior because deep down people have passions and drives that don't lend themselves to systemic modeling.
A systemic model of design error causation is then propagated.
This systemic model leads to four axes: employment, pay, promotion, and participation: 1.
The effect of various operating parameters on the behavior of the DMFC stack is evaluated by the systemic model.
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