Sentence examples for systemic mechanisms from inspiring English sources

Both mechanical and systemic mechanisms have been put forth to explain the effect of obesity on hand OA, but the reason for this association is currently unknown [ 24].

It is concluded that GLP-1 may modulate the function of the hypothalamo-neurohypophysial system as well as the cardiovascular system through both the central and systemic mechanisms.

This question is also linked with the question about anatomical location of NAMO (note that anatomical location of the FA center is still unknown [ 14]: is it in the central nervous system, in visceral organs or in both? Systemic mechanisms suggest periodic changes in concentration of some factor(s).

Although it is known that (post-MI) ventricular dysfunction is the by-product of the large-scale, dynamic interaction of complex molecular systems, there is a lack of understanding of systemic mechanisms that can aid in the prediction and treatment of this disease.

Optimized, rational therapeutic regimens, which to date are essentially empirical, need to address both the underlying cellular processes at the molecular level as well as the systemic mechanisms operating within the complex environment of the central nervous system.

This may reflect differentiated impact of cellular and systemic mechanisms of tolerance in arteries of different size and origin.

Elevated adiposity has been proposed as an under recognised risk factor for all tendinopathies 11 suggesting a systemic mechanism is involved rather than mechanical overload.

It accounts for three different mechanisms of the termination of nucleation and growth: the geometric mechanism by surface exhausting, the stoichiometric mechanism by the consumption of active surface sites and the systemic mechanism by the time dependence of the supersaturation of the initial phase as the thermodynamic driving force of the phase transition.

The breadth of improvements reflects the systemic mechanism of action of ivacaftor compared to other therapies.

It is suggested that CF101 effect is tumour nonspecific and that a general systemic mechanism is induced.

The breadth of improvements reflects the systemic mechanism of action of ivacaftor compared to other (symptomatic) therapies.