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The composition of the paint was notified to value the risk of a systemic intoxication.
The high sensitivity of the IPCR assay allowed the evaluation of the toxicokinetic behavior of ricin following systemic intoxication in mice.
To determine the toxicokinetics of ricin following systemic intoxication, we applied this IPCR method to analyze collected sample sets of at least 5 mice challenged iv with a 5 µg/mouse dose or about 33 mouse LD50's of ricin.
In this study, we applied the novel IPCR assay to monitor the distribution dynamics of ricin after oral or systemic intoxication, determine the biologic half-life of ricin in sera, and evaluate the potential to use feces or sera as diagnostic samples for ricin intoxication.
In rare cases, Cd-containing dental alloys may lead to systemic intoxication (Borowiak et al. 1990).
The inclusion criteria were admission within 24 hours of ingestion of OP and signs of systemic intoxication.
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Although no local anesthetic systemic toxicity was noted during our review of the medical records, it cannot be excluded that central nervous system intoxication during the postoperative period was mistakenly missed and treated as the residual effects of general anesthesia.
The inspection focused on the presence of ash-colored skin, which can occur in argyria (systemic silver intoxication).
1 Idiopathic aetiology was defined as the absence of any other known aetiology including bacterial (purulent), myocardial infarction or Dressler syndrome, hyperuricaemia, neoplasm, systemic disease, intoxication and trauma. 1 Patients with acute pericarditis caused by one or more of these aetiologies were excluded.
The determination of in vivo toxicokinetics and pathological effects of ricin following systemic and oral intoxication provide a better understanding of the etiology of intoxication and will help in the future design of more effective diagnostic and therapeutic methods.
Improvements on the toxicokinetics measurements and the determination of pathological effects of ricin following systemic and oral intoxication will provide a better understanding of the etiology of intoxication.
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