No other systemic findings in the cardiovascular and muscular systems were identified in any of the affected members.
To investigate the frequency and types of systemic findings in patients with apparently isolated uveal coloboma.
If the patient has more systemic findings (e.g. fatigue) and extensive involvement immunosuppressive medications (e.g. prednisone, azathioprine and methotrexate) may be used.
However, lack of other systemic findings and constitutional complaints, as well as negative imaging studies, did not support a diagnosis of malignancy.
Clinical and systemic findings suggest Wegener's granulomatosis.
Lab investigations related to ocular and systemic findings were also analyzed in detail.
Supportive systemic findings, which may include syphilitic chancre, should be investigated and are easily detected upon careful examination.
It is typically a unilateral process without associated systemic findings, usually idiopathic, although it is sometimes found in rare systemic syndromes and genetic disorders.
The diagnosis of bilateral nodular scleritis and sclerokeratitis in OD was made; because of the clinical and systemic findings, Wegener's granulomatosis was considered, and high-dose steroid treatment was begun after infectious causes were ruled out.
Observation of RPE abnormalities in the context of suggestive systemic findings should prompt mtDNA testing.
