Sentence examples for systemic enhancement from inspiring English sources
A knowledge engineering case study has been included to illustrate the systemic enhancement and the results for the OL application under a specific domain using this novel framework.
Microbubbles are less than 10 μm in diameter so they can be intravenously injected to cross the lung bed producing a systemic enhancement.
Moreover, it is very likely that the systemic enhancement in insulin sensitivity, with increased Akt activity in muscle and adipose tissue in addition to the liver, leads to an overall improved metabolism of C2βD1212A/D1212A mice, which reduces the development of hepatic steatosis as a consequence.
On the other hand, undifferentiated arthralgias according to rheumatologic guidelines [ 12- 14], which represent the hallmark of CHIK-R, should be considered for specific involvement in systemic inflammation and enhancement of MetS, assuming these two risk factors are key issues in the increased incidence of cardiovascular diseases occurring among IRD patients [ 40].
When hypoxia was further augmented to FIO2 = 0.115, there was no rhEpo-induced enhancement of systemic V̇O2max or peak leg V̇O2.
Previous clinical trials using injections of GM-CSF protein as an adjuvant have been largely disappointing with some trials showing no enhancement of systemic T cell or serological immunity to co-delivered vaccines [62], [63] although these trials did not assess mucosal responses.
For example, when systemic insulin increases, an enhancement of systemic cytokines occurs [ 11– 13], whereas if insulin concentrations are kept stable with a hyperinsulinaemic euglycaemic clamp, no effect on the systemic cytokine response occurs [ 14, 15].
The enhancement in systemic exposure of PAC loaded solid-nanoemulsion preconcentrate is due to increase in permeability of drug as lipidic nanocarrier as well as inhibition of P-gp mediated effluxing by formulation excipients.
A phase II trial of an intratumoral IL-12 plasmid for unresectable melanoma treatment suggested that local treatment was well tolerated, with no more than grade 2 irAEs, and could induce an enhancement of systemic antitumor immunity.
The effects of the combination treatment with dendritic cells and anti-TGF-β antibody on the enhancement of systemic immune responses and inhibition of metastatic tumor growth were investigated in a murine osteosarcoma (LM8) model.
However, the effect of rhDAF on local cytokine attenuation in the cortex could be due to both the inhibition of cytokine synthesis via the interruption of C3a-C3aR engandmenthendecreasecrease of extravasation of systemic cytokines through the enhancement of BBB integrity.
