Sentence examples for systemic elimination from inspiring English sources

Since paclitaxel was given intravenously, alterations in plasma pharmacokinetics are attributed entirely to alterations in paclitaxel distribution and/or systemic elimination.

We hypothesized that the Co-hArgI enzyme would decrease tumor burden by systemic elimination of L-arg in a murine model.

Conversely, smaller, actively targeted NPs (< 20 nm in diameter) penetrate well into the tumor mass, but are limited by their rapid systemic elimination.

Our analysis also revealed that both age and sex were statistically significant covariates for the systemic elimination rate constant (k).

Recent studies have discussed poor bioavailability of curcumin because of poor absorption, rapid metabolism, and rapid systemic elimination.

Recent studies have discussed poor bioavailability of curcumin because of poor absorption, rapid metabolism, and rapid systemic elimination [ 17, 18]; however, comprehensive pharmacokinetic data are still missing.

Prediction methods for clearance is by far the most studied case because of its importance for systemic drug elimination and oral bioavailability.

Systemic CL and elimination half-life did not differ according to CRRT dose, and so the CRRT prescription may not be useful for guiding antibiotic prescribing.

It was not determined from their study whether the effect of the chemotherapy was as a radiation sensitiser or as a systemic chemotherapy with elimination of possible micrometastasis, or both.

In addition the high rate of failure in terms of distant metastases, suggests that residual malignant cells either in the primary site or elsewhere may require more effective and additional systemic methods of elimination if cure is to be achieved.

In this respect, camouflaged vehicles revealed a delayed elimination from systemic circulation and an improved target organ deposition.