Sentence examples for systemic efficacy from inspiring English sources

However, chemical instability, low bioavailability and poor pharmacokinetic profile limit systemic efficacy of 5-ALA.

However, they rarely show systemic efficacy in animal models when added at non-toxic doses.

This low systemic exposure can provide a potential tool to differentiate topical (lung) vs systemic efficacy and side effects.

Thus, improved discernment of pulmonary vs. systemic efficacy remains a key element to the development of new drugs with better safety profiles.

The lower systemic exposure observed via nanosuspension aerosol delivery will help researchers further explore the feasibility to differentiating topical (lung) vs systemic efficacy and side effects pre-clinically.

Neutrophil infiltration in broncoalveolar lavage fluid and cytokine production in whole blood were measured to assess pulmonary efficacy versus systemic efficacy.

Comparison of systemic corticosteroids' efficacy involved 722 patients who received treatment and 609 controls.

To improve systemic antiviral efficacy, C peptides, which are efficient inhibitors of HIV-1 entry, were engineered for high-level secretion by genetically modified cells.

A small animal model that permits rapid preclinical evaluation of potential candidates for their systemic PrEP efficacy will greatly enhance progress in this area of investigation.

This indicates that local response to therapy must not be representative for systemic treatment efficacy.

The challenge is to integrate a new active agent to enhance the systemic control efficacy of neoadjuvant treatment.