Sentence examples for systemic disruption from inspiring English sources
The theoretical proposition is explored in the context of sustainable Product Service Systems (sustainable PSS), given the opportunities they pose for systemic disruption as radical innovations and the cultural barriers for their mainstream adoption.
These data demonstrate that systemic disruption of Ptk6 results in a dramatic reduction in ERBB2-induced tumorigenesis in vivo.
The NDUFS4 subunit was undetectable in all Ndufs4 fky/fky primary cell types examined, consistent with the systemic disruption of NDUFS4 in the mouse and in keeping with previous reports on all tissues studied [ 12].
Experiment 2 had two objectives: (i) to see if the short latency responses seen in rats in Experiment 1 were also present in mice; and (ii) if so, to see if responses were affected by systemic disruption of neurovascular coupling via inhibition of nNOS.
Especially when integrated with experimental validation, GRNI can be a powerful tool in understanding how regulatory networks are disrupted and rewired, identifying novel regulatory interactions as well as broader systemic disruptions in key oncogenic processes.
Rubin did not think the fund's fall would lead to "systemic disruptions".
The Apc Min/+ mouse demonstrates a sustained and persistent weight loss over at least 4 5 weeks (Puppa et al., 2011a; White et al., 2011b) that provides a model for physiologic examination of systemic disruptions, such as hypogonadism.
One of the concerns would be that undesired and unexpected systemic immune disruption might occur after systemic administration of these agents.
ALI/ARDS is characterized by systemic inflammation, disruption of endothelial and alveolar epithelial barriers, and an increase in microvascular permeability, resulting in pulmonary edema and respiratory failure.
Our findings demonstrate that both systemic and somatic disruption of circadian rhythms contribute to cancer progression.
Also, in the course of the systemic inflammation the disruption of various regulatory axes occurs, including chemokines (VEGF, HGF) and complement proteins (C5a,C3a).
