Sentence examples for systemic challenges of from inspiring English sources

In stark contrast to the public yet artificial perfection of Beijing's Olympics stand the substantial civic and systemic challenges of past events in Atlanta and Athens.

Besides that, we have systemic challenges of risk-aversion rampant at the moment, with venture capitalists behaving like bankers, and Wall Street's obsession with quarterly results that discourages long term R&D.

We demonstrate that the VSVΔG/ZEBOVGP vaccine given 28 days pre-challenge either intranasally (IN), orally (OR), or intramuscularly (IM) protects non-human primates against a lethal systemic challenge of ZEBOV, and induces cellular and humoral immune responses.

The main stimulus for PCT induction is probably a systemic challenge of the organism with bacterial endotoxin (bacterial lipopolysaccharides) [ 2].

To conclude, a systemic challenge of LPS led to an exacerbated and decrease in burrowing activity in 21 month old mice when compared to 4 month old mice.

The existence of an alternative receptor might explain the marginal difference we observed in animal viability between wild-type and NG2-knockout mice during the systemic challenge of TcdB.

Pain response assessed by withdrawal threshold (Z axis) is plotted versus the inflammation measured by ankle diameter (Y axis) for the same rats over days 21 29 following i.v. systemic challenge of SCW (X axis).

A systemic challenge of LPS not only results in cytokine production, but also in increased production of lipophilic molecules including prostaglandins (PGE2), leukotrienes, and thromboxanes, which can all contribute to behavioural changes.

We show that the drugs tested in our study all reduced the hypothermic response to a systemic challenge of LPS, inhibited COX-2 expression in the hippocampus and inhibited PGE2 levels in the hypothalamus.

There was no statistically significant difference in the quantity of L. monocytogenes isolated in liver and spleen tissues following a standard systemic challenge of 104 CFU among groups (n = 10 per group) of RAGE+/+ mice, RAGE-/ mice, RAGE+/- mice, or BALB/c mice given anti-RAGE mAb.

These situations are posing systemic challenges to the reliable operation of the interconnected grid [2].