Sentence examples for systemic balance from inspiring English sources

One should bear in mind the complexity of such challenge as lipids are regulated systemically and their levels reflect complex systemic balance, therefore their pathways generally involve multiple tissues and complex dynamics [ 39].

The dual role of this element has led to the evolution of an elegant regulatory system that maintains iron homeostasis and contributes to its systemic balance [ 2– 4].

In these situations, ScvO2 levels do not reliably reflect the 'true' systemic balance between oxygen delivery and demand.

Alteration of the systemic balance of cytokines has been studied by blocking TNFα and IL-1β using biological agents such as anti-TNFα or IL-1 inhibitors [ 39].

Acupuncture improves reversible malfunctions of the body via direct activation of various brain pathways and thus contributes to the restoration of normal systemic balance, probably due to regulation of neurotransmitters, including Ach [ 30].

Despite the fact that the oxygen extraction ratio, SvO2 or ScvO2 could in theory be a good monitor of the systemic balance between global DO2 and consumption and of the favorable effects on morbidity, pooling of studies using GDT guided by these variables did not demonstrate beneficial effects on mortality [ 12, 13].

However, such actions might be indirect, reflecting drug effects on other targets such as the endocrine system or the BBB, or effects on total brain extracellular volume or systemic electrolyte balance controlled by the kidney.

AMPK controls systemic energy balance and metabolism and has been found to improve endothelial function and reduce cardiovascular risk in diabetic patients148.

However, much further work is required in studying the effects of chronic cannabinoid treatment on these functions in animals at different levels of systemic energy balance.

This review also explores the interaction between HJV, the BMP-SMAD signaling pathway and other regulators of hepcidin expression in systemic iron balance.

Two brain areas are prominent in these processes – the hippocampus, which is involved in aspects of cognitive function and the hypothalamus, the center for the regulation of systemic energy balance.