Sentence examples for systemic administrations from inspiring English sources

The animals received systemic administrations of CUR daily for 21 days.

These structures have low transformation efficiency and slight risk of toxicity at high-dose applications which are considered as promising vectors for systemic administrations.

Strategies for delivering drugs to the posterior segment most often consist in topical ocular medications or systemic administrations, but dose/response profiles are generally very poor.

Several adjuvants used in systemic administrations (either licensed or in clinical trials) are developed with immunostimunlants combinations such the adjuvant system series (AS01, AS02, AS04, AS15) from GlaxoSmithKline containing two or more components of alum, MPL, QS21 or CpG.

Systemic administrations of both the immediate metabolic precursor of KYNA, l-kynurenine (l-KYN), and a proved inhibitor of KYNA's brain transport, probenecid (PROB), have shown to produce neuroprotective effects in a considerable number of experimental toxic conditions; however, this strategy has not been tested in the toxic model Aβ peptide so far.

For inducing the chronic restraint stress, rats were kept in the restrainers for 1 h every day, for 21 consecutive days, then, the animals received systemic administrations of vehicle (0.1% DMSO) acted as the control group or safranal daily for 21 days.

For systemic administration, novel delivery systems are required to confer "drug-like" pharmacokinetic and pharmacodynamic properties.

Systemic administration of this nanocarrier system demonstrates its ability to overcome obstacles met under physiological conditions.

Treatment consists of keeping the affected areas clean and local or systemic administration of antibiotics.

Compared with systemic administration, polymeric controlled release gives higher drug concentration with reduced systemic toxicity.

Two cases of drug delivery are investigated: systemic administration & polymer-based controlled release.