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For systemic administration, novel delivery systems are required to confer "drug-like" pharmacokinetic and pharmacodynamic properties.
Treatment consists of keeping the affected areas clean and local or systemic administration of antibiotics.
Two cases of drug delivery are investigated: systemic administration & polymer-based controlled release.
Compared with systemic administration, polymeric controlled release gives higher drug concentration with reduced systemic toxicity.
AuNP delivery can be accomplished by systemic administration (intravenous injection).
For this application, systemic administration of nanodrugs is possible.
Yet systemic administration of IL-12 is toxic.
Also, dNPA displays anti-opioid activity after systemic administration.
Systemic administration of 3-nitropropionic acid (10 mg/kg i.p).
Systemic administration of CGRP and sumatriptan caused no changes in neuronal activity of the visual cortex.
After systemic administration, mice were killed and different organs were removed and weighted.
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