Sentence examples for systematically substituted by from inspiring English sources

To generate MM sequences, bases were systematically substituted by inversion as follows: A → T, C → G, G → C, and T → A. On each array, genes were represented by an identical number of oligos to minimize bias.

We have systematically substituted these and nearby amino acids by others expected to affect the hydrolysis of pyrethroid insecticides.

In another study, N-oxalyl d-cysteine (DNOC) and a set of histone H3 peptides systematically substituted with cysteine residues were screened by techniques including non-denaturing mass spectrometry for binding to KDM4A and other KDM4 subfamily enzymes.

We systematically substituted a CpG dinucleotide at each position in the consensus p53 DNA binding sequence and identified substitutions tolerated by p53.

These residues were systematically substituted in the Mycobacterium tuberculosis IPMS, resulting in changes in substrate specificity.

The photophysical behavior of a series of flexible di-2-pyridylaminomethyl substituted ligands systematically substituted on a rigid benzene core and their corresponding mono-metallic Re(I) complexes have been investigated by steady state and time-resolved fluorescence spectroscopy in different composition of DMSO water binary solvent mixtures.

It can then be systematically substituted to other methods to analyze data streams, in all cases in which the data points are not too much high dimensional.

Using this procedure, we systematically substituted a 24-bp linker sequence for sequential 45 bp of endogenous espD sequences.

When these histidines are systematically substituted with alanines it is possible to dissect their individual contribution to the overall toxicity.

To detect regions in which the helix may be transiently disrupted during the nucleotide-addition cycle, Weinzierl [ 7] systematically substituted proline at every position in the helix.

All possible pairs of residues in the molecular structure of RG13 (PDB ID: 4DXC) were systematically substituted with cysteines, and disulfide bonds were predicted using SCWRL 4.1.