Exact(3)
Here we show that a wide spectrum of agonists for various TLRs administered systematically inhibits both allergic and autoimmune responses extending in a comprehensive fashion previous isolated reports.
However, it is not yet clear if the overexpression of these genes systematically inhibits cell growth.
We have previously shown, using a large set of breast cancer cell lines, that BMP4 treatment systematically inhibits proliferation in all cell lines and simultaneously increases migration of MDA-MB-231, MDA-MB-361 and HCC1954 cells, but reduces migrativeness of T-47D cells [ 10].
Similar(57)
By systematically inhibiting specific RNA molecules and then revving up the Hedgehog pathway, the researchers could see whether a gene was necessary for the pathway to function.
We perturbed the EGFR signaling pathway model by systematically inhibiting each reaction completely and partially, as described below.
In the light of the results of earlier studies [ 7, 11], we decided to investigate whether highly urban environments systematically inhibited route learning, by re-analysing in detail the relationship between how well birds recapitulate their habitual routes and the visual properties of the landscape.
When administered systematically, Met-CCL5 inhibited eosinophil recruitment into sites of allergic inflammation in mouse skin by 68% [17].
Gradinaru and colleagues used optogenetics to systematically drive or inhibit an array of distinct circuit elements in freely moving parkinsonian rodents and found that therapeutic effects within the subthalamic nucleus can be accounted for by direct selective stimulation of afferent axons projecting to this region [ 47].
Given that EtOH, similar to pharmacologic mTOR inhibitors, inhibits mTOR signaling, we systematically explored the effect of EtOH and INK128 on mTOR signal transduction, components of the mTORC1/2 interaction and their downstream effectors in DLBCL malignancy.
These signaling pathways either activate or inhibit bud formation and systematically regulate fate decision for skin appendages.
We hypothesized that triptolide induced apoptosis in CCA cells by inhibiting Mcl-1, and then systematically tested our hypothesis.
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