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We have described new and up-to-date MMP-based data sets comprising activity cliffs, SAR transfer series, and second generation retrosynthetic MMPs that have been systematically generated from currently available public domain compounds with high-confidence activity data.
Putting together all this information the different ways to perform a modification can be systematically generated and studied.
Moreover, from the graphical model analytical redundancy relations are systematically generated to detect and isolate faults in the process.
It requires a strong will for writers to process all the online hatred directed at them, especially when the worst of it is systematically generated by people you know, operating under a multitude of translucent pseudonyms.
Vividly described by Roger Martin in "The Innovation Catalysts," this process requires as much grit and persistence as systems thinking, bringing to mind Schrage's warning that even systematically generated design cultures are hard to pull off.
Importantly, the NNA allows several network designs, all achieving the minimum resource target, to be systematically generated depending on the order in which the demands are satisfied.
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The smallest observable voxel was determined by systematically generating rectangular prisms and cubes of varying volumes (Supplementary Fig. 15).
Yet students tend to hold preconceptions and misconceptions about causality that hinder learning and systematically generate misconceptions in science content.
When resolved in a coarse grid instead, they systematically generate homogenized algorithms.
It combines heuristics with flowsheet simulations to systematically generate and compare alternatives.
We also show how to explore space of shapes and how to systematically generate new shapes.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com