Sentence examples for systematic discontinuation from inspiring English sources

In contrast, systematic discontinuation programs are more intensive in nature; patients gradually discontinue BZD dose under the guidance and follow-up care of a GP [ 21, 27, 28].

Our study suggests that the lesser morbidity associated with continuation of ongoing statin therapy (as compared with systematic discontinuation) in patients with severe sepsis or septic shock may be influenced by confounders.

Because other factors could increase the diarrhoea risk, diarrhoea onset in ICU patients treated with EN must not be systematically considered a nonfunctionality of the gastrointestinal tract and should not lead to the systematic discontinuation of EN.

Because other factors could increase the diarrhea risk, diarrhea onset in ICU patients receiving enteral nutrition must not be systematically considered a non-functionality of the gastrointestinal tract and should not lead to systematic discontinuation of enteral nutrition.

The first is an educational intervention reinforced by a systematic discontinuation program with follow-up visits, and the second is an educational intervention reinforced by written support; both will be compared with routine care.

We expect that the combination of an educational intervention (reinforced by written information) and an individually tailored tapering program will achieve a discontinuation rate not much lower than that of a systematic discontinuation program with follow-up visits, and will consume less professional time.

A recent systematic review of biological discontinuation studies highlighted the need for a standardised failure definition to reduce the heterogeneity in future studies, but also noted that typical practice studies from registers likely need to rely on broader definitions.

A systematic review of catheter discontinuation strategies for hospitalized patients reported that the intervention of a "stop order" to facilitate prompt removal of unnecessary catheters reduced the duration of catheter use by 1.06 days, and use of either catheter reminders or stop orders decreased the CA-UTI rate by 53% [ 60].

For each treatment, clinic and patient predictor of discontinuation reported in the systematic review, we noted how many studies investigated it and, from these, how many found a statistically significant positive and/or negative association with discontinuation from treatment.

Company clinical trial reports potentially provide an ideal source of information for systematic review and meta-analysis, particularly on discontinuation rates for different causes [ 15, 16].

A systematic literature review reported that rates of discontinuation for toxicity in those taking MTX ranged from 10%to37%7%, with the most common adverse events (AEs) involving the gastrointestinal tract, liver, skin/hair, central nervous system, lungs, as well as cytopenias.