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Systematic and computational analysis of microRNAome and experimental validation collectively showed that miRNAs, ta-siRNAs, and possibly nat-siRNAs play important roles in chilling response and chilling acclimation in Cassava by regulating stress-related pathways, e.g. Auxin signal transduction.
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We perform a systematic theoretical and computational investigation of phenoxazine (POZ -based organic dyes to rationalize the marked difference in the energy conversion efficiency.
Systematic experimental and computational approaches have led to the identification of ∼92 small RNAs (sRNAs) in Escherichia coli K12 MG1655 alone [1].
Therefore, systematic experimental and computational approaches will be invaluable in teasing apart the many combinations of factors required to enact a full AIR.
Both sample acquisition and subsequent analysis are automated in high-throughput instruments, which has continuously posed challenges on the systematic storage and computational processing of the gathered experimental datasets, starting in the early 2000s.
In this study, we have performed systematic and rigorous computational analyses of human aaRSs disease-associated mutations to evaluate their evolutionary, structural and functional characteristics.
Systematic mutational analysis and computational modeling also supported the rationale used in the design.
These and the other pertinent issues will be investigated in this study from the viewpoint of systematic computer code development and computational efficiency, which is substantial to practical engineering applications.
As the method utilizes general and systematic computational procedures, it can be applied to analyze the multi-tone or combination-tone responses for higher-dimensional non-linear systems such as multi-disk rotors or automotive drivelines with multiple excitational inputs.
To do this, we combined systematic design rules, biophysical models, and computational optimization to design synthetic bacterial operons expressing the 5-enzyme pathway, while eliminating undesired genetic elements for maximum expression control.
However, systematic, comprehensive, proteome-scale experimental and computational characterization of protein isoforms directly at the protein/peptide level and with exclusive focus on alternative splicing has never been reported.
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