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Despite the increased dynamical complexity of the resulting system, we demonstrated that precise growth-rate regulation is possible and indeed achievable without the use of sophisticated measurement systems, simply by monitoring a control signal in our turbidostat.
By modifying the ribozyme switch integrated into the system, we demonstrated RNAi-based OFF control devices that respond to small molecule and protein ligands, including the oncogenic protein E2F1.
Additionally, using a PCR-based Cre-loxP system, we demonstrated an increased ability to genetically manipulate the chromosome of C. testosteroni CNB-1.
Using this system, we demonstrated that extracts from highly purified rat liver mitochondria possess the essential enzymatic activity to mediate precise single-nucleotide changes.
Through our prototype system, we demonstrated the feasibility of using such an integrated approach and the study brought insight into applying the proposed domain-independent architecture to different areas of science and engineering in the future.
To conclude, using the yeast expression system we demonstrated that statin treatment introduces significant changes in cell lipid metabolism.
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Finally, to provide an evidence of the quantum nature of our system, we demonstrate the tunability of the dispersive shift by a photon number Nj.
Using a mouse model system, we demonstrate that anergic CD8+ T cells can persist and retain some functional capabilities in vivo, even after the induction of tolerance.
Using TCR V beta 5 transgenic mice as a model system, we demonstrate that the induction of peripheral tolerance can mold the TCR repertoire throughout adult life.
Using this system, we demonstrate that exocytosis from pancreatic β cells and activation of TRPV1 channels are temperature sensitive.
By using a two-machine-quasi-infinite-bus system, we demonstrate that the proposing control effectively damps low-frequency oscillation.
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