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Here, we used collagen gels and exploited the design flexibility of the biological, biochemical and physical characteristics offered by a PEG-based hydrogel system to systematically study the effect of specific extracellular microenvironments on the behavior of primary human fibroblasts in 3D.
For instance, both fracking industry and their cognizant safety oversight agencies should develop a thorough and comprehensive incident/accident reporting and investigation system to systematically address all the root-causes by concentrating on modern human-systems integration methodologies, to disseminate lessons learned, and to avoid the next one.
We have therefore developed a simple system to systematically analyze and record multiple components of pupal eye phenotypes.
Moreover, expression from retroviral vectors in ES cells differentiated in vitro is very inefficient [41], [44], and therefore it is not possible by using the retroviral system to systematically analyse the effects of Lhx2 expression in the ES/EB system.
By integrating biomaterials and tissue engineering strategies, we have developed a novel, mineralized 3-D tumor model and have employed this culture system to systematically investigate the pro-metastatic role of HA under pathologically relevant conditions in vitro.
We have developed a novel mineralized 3-D tumor model and have employed this culture system to systematically investigate the pro-metastatic role of HA under physiologically relevant conditions in vitro.
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One approach is to use model systems to systematically construct complex genotypes and look for combinations that influence phenotype.
To circumvent the lack of control in natural communities, we employed mathematical and experimental systems to systematically investigate how different types of ecological interactions might lead to distinct community patterning.
The implementation of clinical systems to systematically assess and document patient smoking status has been shown to significantly increase the rate at which clinicians intervene with patients who smoke [ 42].
Here we took nonverbal sound as a model system to investigate systematically the physiological and behavioral correlates of processing sensory emotional salience in patients with canonical dementia syndromes.
The overall aim of the assessment of the PHC system was to systematically explore the problems the system faces and the opportunities and barriers for improvement from the perspectives of different actors in the PHC system.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com