For instance, a mathematical model can help identify key drug release mechanisms and uncover the rate limiting processes; allow for the estimation of values of the parameters controlling the system; quantify the effect of the interaction with the biological environment; and aid with the design of optimisation strategies for controlled drug release.
This system quantifies the release of lactate dehydrogenase (LDH) from target cells.
The SOFA score is a scoring system quantifying the extent of a critically ill patient's organ dysfunction or failure, and is composed of six subscores, one each for the respiratory, cardiovascular, hepatic, coagulation, renal and neurological systems [ 29].
For completeness, the Supporting Information Movie illustrates the time sequence of the corresponding intercorrelation matrix, obtained for the hDATdDAT system, quantifying the intercorrelation coefficients between all of the pairs of residues considered in the NbIT calculations.
This system quantifies the degree of inflammation, bone destruction, and cartilage degradation on an arbitrary scale from 0 to 5. The arthritic joints of CIA-affected rhesus monkeys display essentially the same histopathological hallmarks as RA joints.
This system quantifies the degree of inflammation, cartilage damage and bone damage on an arbitrary scale from 0 to 5. Due to the development of neutralizing ADA prior to day 35, followed by the subsequent loss of drug exposure, the data analysis was limited to the period from day 0 to day 31 post induction.
Therefore, the moss technique has been shown to provide a complementary, time-integrated measure of element deposition from the atmosphere to terrestrial systems quantifying the potential availability of potentially harmful substances such as heavy metals [3] or nutrients such as nitrogen [2].
Therefore, the increase of kc1 increases the stability of the system quantified by the barrier heights of oscillation system.
The scoring system quantifies (weigh) the impacts by using a score that reflects their frequency as well as a severity score that indicates the importance of the specific impact in the daily life of the person.
We conducted eight replicate MD simulations (8 ns duration each) of each pH system, and quantified the amount of headpiece opening that occurred.
