Sentence examples for system prompted us from inspiring English sources

The poorly defined factors present in bovine serum, as well as in conditions when feeder cells are used, and the high variability of the embryoid body system prompted us to develop a new, defined, animal product-free differentiation system to generate clinical grade hematopoietic progenitors easily applicable to test the effect of small molecules in large scale screens.

The hypothesis that the dose-limiting side effects of PDE4 inhibitors could be mediated via the central nervous system prompted us to design and synthesize a hydrophilic piperidine analog to improve the side effect profile of Ariflo™ 1, which is an orally active second-generation PDE4 inhibitor.

The altered expression of Th-POK in the absence of Itk, and the elevated Runx3 expression in the low affinity OT-II TCR transgenic system prompted us to determine whether downstream targets of Runx3 are affected in the absence of Itk.

Its immunomodulatory effects, silencing of microglia and the regulatory effects on the endocannabinoid system prompted us to study the effects of R-flurbiprofen in experimental autoimmune encephalomyelitis (EAE) models of multiple sclerosis in mice.

The proposed ancient character of the T. brucei import system prompted us to re-evaluate features of N-MTSs in this flagellate, the enzyme responsible for their processing and the character of the core proteins.

The strong association between FBXO28, MYC and tumourigenesis in the above model systems prompted us to further evaluate if this relationship is important also in the context of primary human tumour cells.

Recently GPR92/LPA5 was identified as an LPA receptor highly expressed by cells of the immune system, which prompted us to investigate its presence and influence on mast cells.

To our knowledge, such a profound inhibition of cell death in S. aureus-infected macrophages is an as yet undocumented event in the in vitro model system and prompted us to elucidate the mechanism(s) of this phenomenon.

During our review of these interfaces, we asked, "What is the underlying model of computation of the interface?" and "How appropriate is the underlying model of the interface in an actor oriented system?" These questions have prompted us to use OpenCV as a driver for a discussion about Dataflow with Marc Geilen (Eindhoven University of Technology) about buffer copying and optimization.

The controversial performance of the rtTA system in neurons prompted us to systematically examine individual components of the Tet system, namely Dox availability across the BBB, rtTA levels and Ptet/Ptetbi activation.

In addition, our interest in evaluating alternative filamentous fungal systems for cellulase expression prompted us to express TrEGI enzymes (wild-type, G230A/D113S/D115T, and G230E/D113S/D115T) in the filamentous fungus N. crassa, which is closely related to T. reesei.