Sentence examples for system mutations in from inspiring English sources
Importin-α3 function has also been examined in the nervous system: mutations in importin-α3 fail to import a synaptic dSmad2 signal into the nucleus and show defects in proper axonal tiling of photoreceptors [11].
In order to identify which HDACs, if any, were involved in FLO1 gene repression in our system, mutations in various HDACs were prepared and screened for FLO1 transcription.
In addition to genes regulating the immune system, mutations in genes affecting epithelial ER stress and function have been associated with IBD risk factors (Khor et al., 2011).
Although genes with repetitive sequences are clear targets in tumours with a defective mismatch repair system, mutations in non-repetitive sequences are also found in MSI tumours.
In the olfactory system, mutations in rn are associated with a loss of ORN classes originating from rn -positive precursors and an expansion of some default rn-negative identities.
The 1 isolate that was negative for all 3 genes carried a single A2059G (Escherichia coli numbering system) mutation in the 23S rRNA gene.
Furthermore, this 'axial' difference in the activities of Hox proteins from the starlet sea anemone is also evident in the degree to which they rescue a nervous system mutation in the bilaterian fly, Drosophila melanogaster.
In these systems, mutations in the FliK homologs YscP [47], [48], InvJ [49] or Spa32 [50] result in the formation of needles of variable length and compromised virulence factor secretion.
Vasen et al. [ 55] hypothesized, '...because of the defect in the MMR system, mutations may accumulate in genes involved in the progression of breast cancer.
Dr. Lane said decades of research had shown that aflatoxins can suppress the immune system, cause mutations in a tumor suppression gene, and prompt tumors in laboratory animals that are similar to tumors found in cigarette smokers.
Beyond its application as a new biological tool for tissue engineering and regenerative therapy, CD133 has highlighted new aspects of the visual system because mutations in the PROM1 gene cause retinal pathologies.
