Sentence examples for system for metabolic from inspiring English sources

These findings will be useful for developing a more reliable gene expression system for metabolic engineering of Clostridium strains.

We used tobacco as a model system for metabolic flux analysis of the equilibrium between PA and anthocyanin synthesis.

FBA can help predict maximum yield, phenotypic changes, effects of gene knockouts, changes in bioenergetics of the system for metabolic engineering, synthetic biology, and biodegradation of xenobiotics [ 57].

A system for metabolic activation of cyclophosphamide (CP), consisting of a crude microsomal fraction of mouse liver and necessary cofactors (S9 mix), was interfaced with three murine cell culture assays for immunotoxicity.

Mu-driven integration of the E. coli transporter gene into the methylotrophic genome was the basis for the development of an efficient method of constructing auxotrophic mutants (Yomantas et al. 2010) with the following exploiting the developed system for metabolic engineering of l-phenylalanine overproduction (Iomantas and Abalakina 2002; Tokmakova et al. 2008, 2010).

Meanwhile, whereas gene expression systems for metabolic engineering have traditionally been static or externally tunable, an expanding toolbox of metabolite-responsive gene regulators coupled with deeper insights into metabolic bottlenecks have given rise to dynamic control over engineered pathways.

It was demonstrated experimentally that the nanoporous aluminum oxide membranes are well suited as substrates in cell culture model systems for metabolic, pharmacological/toxicological research, tissue engineering and studies on pathogens as well as bioartificial liver systems.

Moreover, concepts have been developed to compare relevant in vitro and in vivo concentrations (Bosgra et al. 2012; Krug et al. 2013a; Zimmer et al. 2011a), and to incorporate systems for metabolic activation of drugs (Godoy et al. 2013).

In particular, we used our newly developed system, SORTA, to recode 5210 unique entries for 'physical exercise' in the LifeLines biobank (5) and 315 unique entries for 'physical symptoms' (including terms that are similar, but not the same) in the Dutch CINEAS (www.cineas.org) (6) and HPO Human Phenotype Ontologyy) coding systems for metabolic diseases.

In the development of screening systems for metabolic disruptors in a PoT-based toxicity testing approach, the combination of relevant in vitro models of insulin-sensitive tissues (liver, skeletal muscle, adipose tissue) with an omics approach may be a step ahead (Corvi et al. 2006; NRC 2007a).

Snake mitochondrial function and oxidative metabolism appear to be exceptional system-wide, implying that snakes are an excellent model system for further metabolic research.