The IL-5 concentration in the calibrator included in the MSD™ IL-5 kit was as reported by the manufacturers when analyzed in the assay with the R&D Systems reagents, which was also true for the reverse test (R&D systems calibrator analyzed with the MSD™ kit, Supplemental Fig. I shows similar calibration curves for the MSD™ kit and the assay using R&D Systems materials).
A dose measurement system (Dose calibrator Pet Dose, Comecer) provided measurements of the amount of F-FDG radioactivity (administered and residual) for all phantoms and patient studies.
All devices involved (PET/CT systems, dose calibrators, well counters, clocks, scales) should be maintained according to the manufacturers' recommendations or following national guidelines [ 99 ].
A cross calibration among the SA-PET/CT system, the dose calibrator, and the gamma counter was performed.
It is not easy to design a calibrator system able to reproduce the time and directivity patterns of the acoustic pulse produced in an ultra high energy neutrino interaction.
Cross calibration (between dose calibrator and systems and between the systems) and normalization with time alignment and full detector calibration have been performed on a regular basis according to manufacturer's recommendations on both scanners.
Compliance to these guidelines including clock synchronization, cross-calibration between PET systems and dose calibrator, injected dose and delay between injection and imaging was found to be good in this study of consecutive patients scanned in routine clinical practice.
There is presented the calibration procedure and an example solution of a fully automatic calibration system which employs the three phase Power/Energy Calibrator from Poland, which is traceable to the national standards.
A cross-calibration among the SA-PET/CT system and the dose calibrator was performed.
Remaining activity in the tail was measured on in vivo imaging data because a cross-calibration between the SA-PET system and the dose calibrator was undertaken and because we had previously shown that ex vivo counting (taken as gold standards) and Inveon SA-PET/CT data was well correlated [18].
The system can be calibrated with both a calibration mass, and an electric calibrator.
