Sentence examples for system by targeting from inspiring English sources

Exact(17)

Third, they decided not to game the system by targeting only patients in contracts that would yield financial rewards.

We have previously developed genetically engineered mouse models of brainstem glioma using the RCAS/Tv-a system by targeting PDGF-B overexpression, p53 loss, and H3.3K27M mutation to Nestin-expressing brainstem progenitor cells of the neonatal mouse.

Ipilimumab activates the immune system by targeting cytotoxic T-lymphocyte-associated protein 4 (CTLA-4).

Ipilimumab is a fully human, recombinant monoclonal antibody that activates the immune system by targeting cytotoxic T-lymphocyte-associated antigen 4 (CTLA-4).

References. 1. Materazzi S, Benemei S, Fusi C, Gualdani R, De Siena G, Vastani N, Andersson DA, Trevisan G, Moncelli MR, Wei X, Dussor G, Pollastro F, Patacchini R, Appendino G, Geppetti P, Nassini R. Parthenolide inhibits nociception and neurogenic vasodilatation in the trigeminovascular system by targeting the TRPA1 channel.

We were able to confirm the utility of this delivery system by targeting and decreasing levels of a second slit diaphragm protein found in the podocyte, transient receptor potential channel 6 (TRPC6) [19].

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Similar(43)

Cbl negatively regulates cell adhesion in most systems by targeting α5-integrin, CrkL and FAK for ubiquitination [ 56, 57].

Another ongoing approach for pain reduction is to harness the endogenous cannabinoid systems by targeting fatty acid amide hydrolysis, the major degradation pathway for endogenous cannabinoids [ 50].

The State Farm insurance company has a strong loyalty-based management system, started by targeting the right customers: better-than-average drivers.

He compared such a strategy to the way the development of pharmaceuticals has evolved from trial-and-error to a rational design system that begins by targeting the exact biochemical pathway to be treated.

They are active on a wide variety of insect pests, especially lepidopterans and dipterans, but do not have antibiotic activity.95 The compounds attack the nervous system of insects by targeting two key neurotransmitter receptors, with no cross-resistance to other known insecticides.

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