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Our study suggests that the most accurate data will be obtained from combination of both mouse models in association with multiple imaging modalities since the TH-MYCN system allows testing of the drugs in an immune proficient model while the orthotopic xenograft system uses human cells grown in the proper microenvironment.
This system allows testing of hypothesis as new data comes in.
This system allows testing of static balance time and body sway via measurements from the force platform [ 39].
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Since hybridogenetic unisexuals are often in direct competition with their sexual parental species due to the forced coexistence, such systems allow testing the effects of sex-specific mutations rates on the relative success of sexual versus asexual reproduction.
Models help resource managers develop a shared conceptual understanding of complex natural systems, allow testing of management scenarios, predict outcomes of high risk and high cost environmental manipulations, and set priorities.
Scaleability of the benchmark allows testing systems of different sizes, and simplicity means that the benchmark has to be understandable and thereby credible.
This system includes four independent reporters that allow testing interactions at different stringencies and is being used in our laboratory to establish ab initio wheat protein interaction networks using cDNA Y2H library screening (Yang and Dubcovsky, unpublished).
This allowed testing the repeatability between the two multiplexing systems.
This sensitive in vivo system allows the testing of different proteins for molybdate binding under in vivo conditions and will facilitate the identification of other cellular factors needed for molybdate binding.
The system allows easy testing and calibration of the model for any given area and time of interest, and can be used as a tool for further development of a more comprehensive model for engineering application.
This system allows fatigue tests to be driven up to 100 Hz, reducing the time taken by a factor of ten without detrimental heat being generated in the material.
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