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For this reason, we decided to synthetically modify the natural metabolite, obtaining small arrays of unnatural variants useful to illuminate the structural requirements essential for the activity.
In the course of our investigations we decided to synthetically modify the parent compound to clarify the structural determinants responsible for the activity; in fact, very recently, our research group reported the synthesis and the pharmacological properties of a first collection of PM analogues generated by Ludi approach.
Thereby, it provides an important step to synthetically modify these systems for systems biology approaches.
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11 Although similar strategies have been developed for preparing synthetically modified ubiquitin, 12 these procedures require extensive or specialist synthetic peptide synthesis.
Most antisense RNAs are synthetically modified derivatives of RNA or DNA with potential therapeutic value.
Lee, K. et al. Synthetically modified guide RNA and donor DNA are a versatile platform for CRISPR-Cas9 engineering.
The design and synthesis of synthetically modified cyclic A-site 16S rRNA construct is reported.
We came to the last tub in the room, filled with the telltale yellow: a culture of synthetically modified organisms growing in the open air.
The present study describes an efficient and reliable method for the preparation of MS2 viral capsids that are synthetically modified with antibodies using a rapid oxidative coupling strategy.
That same day, "green" laundry detergent maker Ecover responded to a campaign led by environmental and consumer groups demanding that the company stop using algal oil produced using synthetically modified organisms.
Few synthetically modified isatin exhibited potent inhibitory activity at concentration of 2 μg/disc against Planococcus donghaensis, Erythrobacter litoralis, Alivibrio salmonicida, Vibrio furnisii.
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CEO of Professional Science Editing for Scientists @ prosciediting.com