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11 Although similar strategies have been developed for preparing synthetically modified ubiquitin, 12 these procedures require extensive or specialist synthetic peptide synthesis.
Most antisense RNAs are synthetically modified derivatives of RNA or DNA with potential therapeutic value.
Lee, K. et al. Synthetically modified guide RNA and donor DNA are a versatile platform for CRISPR-Cas9 engineering.
The design and synthesis of synthetically modified cyclic A-site 16S rRNA construct is reported.
We came to the last tub in the room, filled with the telltale yellow: a culture of synthetically modified organisms growing in the open air.
The present study describes an efficient and reliable method for the preparation of MS2 viral capsids that are synthetically modified with antibodies using a rapid oxidative coupling strategy.
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For this reason, we decided to synthetically modify the natural metabolite, obtaining small arrays of unnatural variants useful to illuminate the structural requirements essential for the activity.
In the course of our investigations we decided to synthetically modify the parent compound to clarify the structural determinants responsible for the activity; in fact, very recently, our research group reported the synthesis and the pharmacological properties of a first collection of PM analogues generated by Ludi approach.
These problems could be resolved in two ways: synthetically modifying the structure or finding new formulations with enhanced properties.
These problems could be resolved in two ways: synthetically modifying the titanocene structure (laborious, other physico-chemical and biological analyses needed) or finding new formulations with enhanced properties [11, 13, 15, 19, 24 27].
Thereby, it provides an important step to synthetically modify these systems for systems biology approaches.
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