Sentence examples for synthetic screen from inspiring English sources

We performed a synthetic screen to identify nonessential genes with a synthetic sick or lethal relationship in cells with low abundance of nuclear Pif1.

Reviewer #1: The authors identified chromatin remodellers and chromatin modifiers in a synthetic screen analyzing mutants of Pol II CTD serine 2 (S2andand the CTD S2 kinase lsk in S. pombe.

Additionally, splicing factors were isolated in synthetic screens for the enhancers of germline overproliferation phenotype in the sensitized backgrounds of weak glp-1 (gf) (Mantina et al. 2009; Kerins et al. 2010; Wang et al. 2012).

For these reasons, secondary screens that address these questions are required when the goal of a synthetic lethal screen is to identify new drug targets.

The synthetic lethal screen is generally employed to identify genes encoding proteins that function in a parallel pathway or with overlapping functions within an essential pathway.

In a RNA interference (RNAi -based synthetic lethal scRNAi -basedg paclitaxel chemosyntheticr genes in a human NSClethall line, proteascreenseekingost enriched gene groupaclitaxel

We designed a novel approach to perform a synthetic lethal screen aimed at uncovering more precisely the function of Rps15p in ribosome biogenesis.

Thus, a synthetic lethality screen that uses a spindle checkpoint mutant should identify genes whose functions are monitored by the spindle checkpoint.

A previous study used a synthetic lethality screen to discover genes that genetically interact with temperature sensitive mutations in the ORC2 and ORC5 subunits.

We have designed a synthetic lethal screen in Saccharomyces cerevisiæ to identify its genetic partners and further elucidate its role during ribosomal biogenesis.

Trf4 and Trf5 were originally isolated in a synthetic lethal screen with top1 mutations.