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On the basis of these results, reduction mechanism is discussed and also the synthetic scope is described.
This article summarizes for the first time the advances in understanding and synthetic scope of CMRP since its discovery.
The approach of combining structure-guided enzyme engineering with efficient mutant library screening has extended the synthetic scope of these enzymes in recent years and has resolved important mechanistic issues for AMs and ALs, including those containing the MIO (4-methylideneimidazole-5-one) internal cofactor.
(2) Subsequently, we studied the synthetic scope of the reaction (Table 2).
With the optimization results in hand, we studied the synthetic scope of the aminocyclization reaction in detail (Table 2).
The synthetic scope and a preliminary mechanistic study for both the inter- and intramolecular arylations are discussed.
Similar(47)
Intelligent landscape navigation, informed by sequence-activity relationships and coupled to the emerging methods of synthetic biology, offers scope for the development of novel biocatalysts that are both highly active and robust.
This synthetic strategy provided the scope to generate a range of products with subtle substituent differences in order to help rationalise any variations seen, between individual compounds, in either the rate of NO release or biological profile.
This is an important issue when creating synthetic speech in the scope of machine-user communication.
Although the number, power and scope of synthetic reactions has increased significantly in recent times, the time and effort required to synthesise molecules has not.
Fundamentally new, and potentially scaleable, modes of gene regulation have been created that enable expansion of the scope of synthetic circuits.
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CEO of Professional Science Editing for Scientists @ prosciediting.com